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A novel anti-rheumatic drug, T-614, stimulates osteoblastic differentiation in vitro and bone morphogenetic protein-2-induced bone formation in vivo

โœ Scribed by Kohji Kuriyama; Chikahisa Higuchi; Keiichi Tanaka; Hideki Yoshikawa; Kazuyuki Itoh


Book ID
117052991
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
448 KB
Volume
299
Category
Article
ISSN
0006-291X

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This study rcports that recombinant adenovirus-mediated human bone morphogenetic protein-2 gene transfer can induce mesenchymal progenitor cell dillerentialion and bone formation. The recombinant adenovirus with the human hone morphogenetic protein-2 gene was constructed, and mature human bone morph