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A novel and convenient synthesis of thiazolo[3,2-a]pyrimidin-7-ones and pyrido[1,2-a]pyrimidin-2-ones using Vilsmeier reagent

โœ Scribed by Yi Yi Weng; Lei Ming Ying; Qi Xu Chen; Wei Ke Su

Book ID
116350373
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
227 KB
Volume
23
Category
Article
ISSN
1001-8417

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A convenient synthesis of trisubstituted
A convenient synthesis of trisubstituted pyrido[2,3-d]pyrimidin-7-ones
โœ Jiri Kasparec; Jerry L. Adams; Joseph Sisko; Domingos J. Silva ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 99 KB

A novel, highly efficient and scalable route for the synthesis of trisubstituted pyrido[2,3-d]pyrimidin-7-ones was developed. The target compounds were synthesized in five steps from readily available reagents in about 40% overall yield.