A novel and convenient synthesis of dibenz[a,c]anthracene
β Scribed by Harvey, Ronald G.; Leyba, Cynthia; Konieczny, Maria; Fu, Peter P.; Sukumaran, K. B.
- Book ID
- 120742068
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 459 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
An unequivocal synthesis of dihydrodiols of the mutagenic polycyclic aromatic hydrocarbon, dibenz(a,c)anthracene is described An important aspect of polynuclear aromatic hydrocarbon (PAH)-induced carcinogenesis concerns the mechanism by which these relatively inert molecules are metabolically activa
The concomitant synthesis of dibenz(a,c)anthracene l,Z-oxide (8) and benz(a)anthryl (5.6-f) oxepine ( 9) from a common dibromoacetate precursor, and photoisomerization of arene oxide (8) to the oxepine ( 9) y& an oxygen walk mechanism occurs in accord with predictions.