A novel, alternative pathway of apoptosis triggered through class II major histocompatibility complex molecules
β Scribed by ZoltanA. Nagy; NualaA. Mooney
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 333 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0946-2716
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## Abstract Complexes of major histocompatibility complex (MHC) class II molecules containing invariant chain (Ii)βderived peptides, known as class IIβassociated invariant chain peptides (CLIP), are expressed at high levels in presentationβdeficient mutant cells. Expression of these complexes in mu
We studied major histocompatibility complex class II-dependent presentation of two T cell epitopes delivered as synthetic peptides by fixed macrophages. Treatment of bone marrow macrophages with inhibitors of proteinases of the metallo-, aspartic and serine proteinase families enhanced presentation