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A novel algorithm for simultaneous SNP selection in high-dimensional genome-wide association studies

✍ Scribed by Verena Zuber, A Pedro Duarte Silva, Korbinian Strimmer

Book ID
120675847
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
238 KB
Volume
13
Category
Article
ISSN
1471-2105

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One of the most difficult issues to be solved in genome-wide association studies is to reduce the amount of genomic DNA required for genotyping. Currently available technologies require too large a quantity of genomic DNA to genotype with hundreds or thousands of singlenucleotide polymorphisms (SNPs