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A Novel Acetylated Analogue of Dynorphin A-(1−11) Amide as a κ-Opioid Receptor Antagonist

✍ Scribed by Wan, Qiang; Murray, Thomas F.; Aldrich, Jane V.

Book ID
126860550
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
67 KB
Volume
42
Category
Article
ISSN
0022-2623

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The tryptophan isomers of the cyclic tetrapeptide CJ-15,208, reported to be a kappa opioid receptor (KOR) antagonist [Saito, T.; Hirai, H.; Kim, Y. J.; Kojima, Y.; Matsunaga, Y.; Nishida, H.; Sakakibara, T.; Suga, O.; Sujaku, T.; Kojima, N. J. Antibiot. (Tokyo)2002, 55, 847-854.], were synthesized t