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Pharmacological properties of JDTic: a novel κ-opioid receptor antagonist

✍ Scribed by Ivy Carroll; James B. Thomas; Linda A. Dykstra; Arthur L. Granger; Richard M. Allen; James L. Howard; Gerald T. Pollard; Mario D. Aceto; Louis S. Harris


Book ID
113585003
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
265 KB
Volume
501
Category
Article
ISSN
0014-2999

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The tryptophan isomers of the cyclic tetrapeptide CJ-15,208, reported to be a kappa opioid receptor (KOR) antagonist [Saito, T.; Hirai, H.; Kim, Y. J.; Kojima, Y.; Matsunaga, Y.; Nishida, H.; Sakakibara, T.; Suga, O.; Sujaku, T.; Kojima, N. J. Antibiot. (Tokyo)2002, 55, 847-854.], were synthesized t