✦ LIBER ✦

A Note on the Tangle Model for DNA Recombination

✍ Scribed by C. Cerf

Publisher: Springer
Year: 1998
Tongue: English
Weight: 140 KB
Volume: 60
Category: Article
ISSN: 1522-9602
DOI: 10.1006/bulm.1997.0024

No coin nor oath required. For personal study only.

✦ Synopsis

The tangle model developed by Ernst and Sumners provides a rigorous framework to study processive DNA recombination. We suggest here a slight modification of that model. The tangle equations become:

where M is the mechanism tangle, and S is the substrate tangle, that is the sum of O (outside tangle) and P (parent tangle). The advantage of this revisited model is that it faithfully models the fact that the recombination mechanism is the same during each event of recombination. This leads to new solutions for O and P, some of which are interesting from a biological viewpoint.

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