𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A note on the mechanism of electroreduction of isoniazid in acidic media

✍ Scribed by José Miguel Rodríguez Mellado; Rafael Marín Galvín

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
162 KB
Volume
37
Category
Article
ISSN
0013-4686

No coin nor oath required. For personal study only.

✦ Synopsis

Ahstraet-The electroreduction of isoniazid was studied at pH < 6. On the basis of polarographic and voltammetric measurements and by regarding the Tafel slopes and reaction orders, it was concluded that in a very strongly acidic medium the rate-determining step of the process is the loss of an ammonia molecule to yield isonicotinamide, whereas at pH > 2 the process is controlled by the second onaelectron transfer, which is irreversible.

📜 SIMILAR VOLUMES

Study of the electroreduction of NAD and
Study of the electroreduction of NAD and NADP coenzymes in strongly acidic media
✍ José Miguel Rodríguez Mellado; Rafael Marín Galvín 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 470 KB

The electroreductions of NAD and NADP coenzymes have been studied in acidic media (5 M H,SO, to pH = 2) by DP and dc polarography. Tafel slopes and reaction orders were obtained from i-E curves traced at potentials corresponding to the foot of the polarographic waves. The results show that, at very

The electroreduction (polarographically)
The electroreduction (polarographically) of uranyl ion in nitric acid and nitric acid-methanol mixture media
✍ M.A. Ghandour; R.A. Abo-Doma; E.A. Gomaa 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 386 KB

The polarographic reduction of uranyl ion in nitric acid solution are found to be one electron reduction mechanism at lower acid concentration (0.1 M HNO,) and two electron mechanism at high acid concentration (2 M HNO,). Methanol shifted the half wave potentials to more negative values and increase