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A nonconditional replication-defective mutant of the Schmidt-Ruppin strain of Rous sarcoma virus

✍ Scribed by Peter K. Vogt; Michael Hayman; Eric Hunter; Peter H. Duesberg

Book ID: 119009841
Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 435 KB
Volume: 92
Category: Article
ISSN: 0042-6822
DOI: 10.1016/0042-6822(79)90133-8

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## Abstract A cytopathic effect was induced by the Schmidt‐Ruppin strain of Rous sarcoma virus (RSV‐SR) in five of nine rat tumor cell lines tested in vitro. The cells showed irreversible cytopathic change as early as 24‐48 h after infection. Of the leukemogenic and tumorigenic viral agents tested,