𝔖 Bobbio Scriptorium
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A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1

✍ Scribed by Hülya Çevik-Aras; Christina Kalderén; Annika Jenmalm Jensen; Tudor Oprea; Claes Dahlgren; Huamei Forsman


Book ID
113489749
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
614 KB
Volume
83
Category
Article
ISSN
0006-2952

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The design and synthesis of non-peptide
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2,4-disubstituted morpholin-3-one based ligands which show affinity for tachykinin receptors have been designed and synthesised. Variation of the side chains attached to the central template gives rise to selectivity between receptor subtypes. This selectivity is directly analogous to that exhibited