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A non-destructive method for the determination of completeness of coupling reactions in solid phase peptide synthesis

✍ Scribed by Linneaus C. Dorman

Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
159 KB
Volume
10
Category
Article
ISSN
0040-4039

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Three peptide-oligonucleotide phosphorothioate hybrids were synthesized using a new approach for stepwise solidphase synthesis of conjugates. This method utilizes commercially available N a -Fmoc amino acids for peptide synthesis and a new solid support. Three specific modifications of the solid-pha