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A non-congener based synthesis of L-(-)-rhodinose and of a C4 hydroxyl protected derivative

✍ Scribed by Richard H. Schlessinger; Deborah D. Graves


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
260 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis


A practical five step construction of the L-(-)-rhodinose derivative 1 and of L-(-)rhodinose (2) from 0-benzyl (S)-ethyl lactate is described.

Optical rotations and other data for both 7 and 2 as well as for intermediates leading to them are provided.


πŸ“œ SIMILAR VOLUMES


Asymmetric synthesis of L-[4-13C]lysine
✍ Kazuhiko Takatori; Akira Hayashi; Masahiro Kajiwara πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 119 KB πŸ‘ 1 views

## Abstract L‐[4‐^13^C]Lysine (**2**) was synthesized from sodium [2‐^13^C]acetate (**3**) and Dellaria's oxazinone **1** as a chiral glycine equivalent. Wittig reaction of the glycinal **7** and ^13^C‐labeled phosphonium ylide **5**, prepared from sodium [2‐^13^C]acetate (**3**), gave the __Ξ±__, _