A new α-selective synthetic equivalent for the crotyl anion in additions to imines
✍ Scribed by Johannes Betz; Manfred Heuschmann
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 196 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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2005 ## Amines Q 0120 Catalytic Additions of Acylsilanes to Imines: An Acyl Anion Strategy for the Direct Synthesis of α-Amino Ketones. -The title methodology enables direct formation of N-phosphinylated amino ketones and completely avoids benzoin formation. The reaction tolerates structural div
## Abstract Double nucleophilic addition reactions of dialkoxy ketenesilyl acetals proceeded with α,β‐unsaturated imines to give 1,4‐ and 1,2‐double addition products, and their subsequent transformations afforded multisubstituted pyrroles in good yields. Application of this procedure to the synthe