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A new type of minocycline-induced cutaneous hyperpigmentation

✍ Scribed by R. W. Mouton; H. F. Jordaan; J. W. Schneider

Book ID
108692426
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
243 KB
Volume
29
Category
Article
ISSN
0307-6938

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## Abstract Alkaptonuria, a rare autosomal‐recessive disorder caused by mutations in the __HGD__ gene and a deficiency of homogentisate 1,2‐dioxygenase, is characterized by accumulation of homogentisic acid (HGA), ochronosis, and destruction of connective tissue resulting in joint disease. Certain