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A New Triterpene and New Sesquiterpenes from the Roots of Ligularia sagitta

✍ Scribed by Ping-Lin Li; Zhong-Jian Jia

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
208 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

One new triterpene and seven new eremophilane‐type sesquiterpenes were isolated from the roots of Ligularia sagitta, among them 1a, an O‐acetylated oleanane type triterpene, 2a and 3a, two 11‐nor eremophilane‐type sesquiterpenes, 4a, 5, and 6, three standard eremophilane‐type sesquiterpenes, and 7 and 8, two tri‐nor eremophilane‐type sesquiterpenes. Their structures were established by extensive spectral analyses (1D, 2D‐NMR, IR, and MS). Compound 1a showed moderate cytotoxicity against two tumor cell lines.

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