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A new technique for labeling of [11C]-choline, a positron-emitting tracer for tumor imaging

✍ Scribed by Zhang Jinming; Tian Jiahe; Wang Wushang; Liu Baoli

Publisher
Springer
Year
2006
Tongue
English
Weight
111 KB
Volume
267
Category
Article
ISSN
1588-2780

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Pyruvate-1-11C was prepared enzymatically by the exchange reaction of 11CO2 with the carboxyl group of pyruvic acid using pyruvate-ferredoxin oxidoreductase from Clostridium butyricum. 11C-Labeled pyruvate was purified by sublimation in specially made glassware. The radiochemical yield of pure pyruv