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A new target for microsatellite instability in gastrointestinal cancer: Microsatellite instability in the insulin-like growth factor ii receptor gene in gastrointestinal tumours

✍ Scribed by Stephen A. Bustin


Book ID
114382065
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
217 KB
Volume
3
Category
Article
ISSN
1357-4310

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Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI