Treatment of 7C-(2,2.3-trihaloalkylideneamino)cephalosporins with excess methanol in the presence of acid scavenger gave 7p-(2-haloalk-2-enylideneamino)-7+methoxycephalosporins.
A new synthetic method for 7α-methoxycephalosporins
✍ Scribed by Satoru Nakabayashi; Eiichi Akita; Katsuyoshi Iwamatsu; Koichi Shudo; Toshihiko Okamoto
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 126 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Since the suggestion by Strominger and Tipper 1) that 6-methyl penicillins and 7-methyl cephalosporins should have enhanced antimicrobial activity, a number of 6 or 7-substituted penicillins or cephalosporins have been synthesized.
Reaction of a-methoxyurethanes with phenylisocyanide gave the corresponding amides of o-amino acid in reasonable yields.
Aromatic glyoxalm and their dorivatirea hare been found te pemmera urkod antiviral (1) actlrity and to some oxtent known aa antitubercular (2) agent\*. substituted phony1 glyoxals hare alme beor umed for the oyntheoio ef cardio-