A new synthesis of α,β-unsaturated γ- and δ-lactones via intramolecular acylation of α-sulfinyl carbanion
✍ Scribed by Manat Pohmakotr; Prapanpong Jarupan
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- French
- Weight
- 170 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0040-4039
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A series of 18 new a,&unsaturated &&&substituted &lactones was synthesized as possible therapeutic agents. The majority of the compounds described contain an aryloxy grou in the pposition of the lactone ring, while those naturally occurring in P+er mat&ticwn all contain an alkoxy group in this posit
A convenient synthesis of 5-methylene-2-cyclopentenones University, including Methylenomycin B involving the intramolecular acylation of cr-sulfinyl carbanion followed by methylation and pyrolysis is described. 5-Methylene-2-cyclopentenone unit occurs widely in natural products, particularly the cyc