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A new synthesis of α-methylserine by nucleophilic ring-opening of N-sulfonyl aziridines

✍ Scribed by Peter Wipf; Srikanth Venkatraman; Chris P. Miller


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
257 KB
Volume
36
Category
Article
ISSN
0040-4039

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Regioselective Nucleophilic Ring Opening Reactions of 2,2-Disubstituted Aziridines -The Asymmetric Synthesis of α,α-Disubstituted Amino Acids. -It is shown that, under appropriate conditions, 2,2disubstituted aziridines like (I) and (V) undergo regioselective ring opening reactions at C-3 with carb