Synthesis of pyrrolo[2,3-d]pyrimidines v
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Charles J Barnett; Lana M Grubb
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Article
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2000
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Elsevier Science
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French
⚖ 62 KB
A series of b-alkoxyand b-amino-a-bromoaldehydes was synthesized. The cyclocondensation of these intermediates with 2,4-diamino-6-hydroxypyrimidine yielded a series of pyrrolo[2,3-d]pyrimidines containing heteroatoms in the side chain. Choice of protecting group proved critical to the success of the