A new synthesis of thes-triazolo[1,5-a]pyridine ring system
✍ Scribed by G. Hajós; G. Timári; A. Messmer; A. Zagyva; I. Miskolczi; J. G. Schantl
- Publisher
- Springer Vienna
- Year
- 1995
- Tongue
- English
- Weight
- 164 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0026-9247
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## Abstract magnified image Synthesis of novel 3‐substituted‐1,2,3‐triazolo[1,5‐a]quinazolinones in high yields was performed __via__ anionic hetero‐domino reaction of appropriate substituted 2‐azidobenzoates prepared from isatines and acetonitriles activated by 1,3‐thiazole, 1,3‐benzothiazole, 1,3
Dianion 2 derived from N-Boc-aminobenzotriazole 1 condenses in a [1.2]fashion with ct, fl-unsaturated aldehydes; subsequent oxidation of the resulting allylic alcohols 7 using manganese(IV) oxide or, less effectively, treatment of the derived acetates 10 with Pd(O), results in direct formation of th