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A New Synthesis of o-Nitrophenylacetaldehyde

✍ Scribed by Noland, Wayland E.; Sellstedt, John H.


Book ID
126153757
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
339 KB
Volume
31
Category
Article
ISSN
0022-3263

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## Abstract Coprine (1), a toxine of the mushroom __Coprinus atramentarius__, was synthesized starting from the 2‐amino and 1‐carboxy‐protected L‐glutamic acids 4 and 12. Compound 4 was first decarboxylated by a radical chain reaction to bromide 5 which underwent ring closure to cyclopropanecarboxy