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A new synthesis of imidazo[1,2-a]pyridine and imidazo[2,1-a]isoquinoline derivatives

✍ Scribed by Yoshinori Tominaga; Shigenori Motokawa; Yoshihide Shiroshita; Akira Hosomi


Book ID
112128706
Publisher
Journal of Heterocyclic Chemistry
Year
1987
Tongue
English
Weight
331 KB
Volume
24
Category
Article
ISSN
0022-152X

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Solid-phase synthesis of imidazo[1,2-a]p
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; GΓ©rald Guillaume πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.