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A new synthesis of (±)-homosarkomycin ethyl ester

✍ Scribed by Ali Samarat; Valérie Fargeas; Jean Villiéras; Jacques Lebreton; Hassen Amri

Book ID
104211732
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
58 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new and efficient synthesis of (±)-homosarkomycin ethyl ester 6, an antitumor antibiotic is described. The successful synthetic approach to 6 uses b-ketophosphonate 5 as a key intermediate.

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