Efficient synthesis of novel carbocyclic
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Ok Hyun Ko; Joon Hee Hong
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Article
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2002
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Elsevier Science
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French
โ 72 KB
Very efficient synthetic route to novel 4%a-C-hydroxymethyl branched carbocyclic nucleosides was described. The stereocontrolled synthesis of target nucleosides was successfully achieved by Johnson orthoester-Claisen rearrangement, ring-closing metathesis (RCM) starting from a simple acyclic precurs