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A new synthesis of ?-amino-acids by the reaction of Grignard reagents with ethyl N-trichloroethylidenecarbamate

โœ Scribed by Kashima, Choji; Aoki, Yoshiko; Omote, Yoshimori


Book ID
120643061
Publisher
Royal Society of Chemistry
Year
1975
Weight
266 KB
Volume
23
Category
Article
ISSN
1472-7781

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Reactions of an electrophilic glycine ca
โœ Arlindo L. Castelhano; Stephen Horne; Roland Billedeau; Allen Krantz ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 199 KB

A simple and general synthesis of a-amino acids employing vinyl and alkyl Grignard reagents with a glycine cation equivalent is described. B,v-Unsaturated a-amino acids are natural products that possess antibiotic activity and enzyme inhibitory properties. 3 Several synthetic B,T-unsaturated a-amino