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A new synthesis of 3-hydroxy-2,3-dihydro-1,4-benzodioxin-2-carboxamides and 3-aminomethylene-1,4-benzodioxin-2(3H)-one derivatives

✍ Scribed by C Bozzo; M.D Pujol; X Solans; M Font-Bardia


Book ID
118549847
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
511 KB
Volume
59
Category
Article
ISSN
0040-4020

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Convenient syntheses of relatively rare 2,2-disubstituted-2,3-dihydro~l,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-l,4-benzodioxins, as key synthetic intermediates, are reported. These new synthetic approaches require Lewis acid BF3-Et20 mediated nucleophilic substitution reaction or cy