Convenient synthesis of 2,2-disubstitute
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Valérie Thiéry; Gérard Coudert; Gérald Guillaumet
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Article
📅
1997
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Elsevier Science
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French
⚖ 664 KB
Convenient syntheses of relatively rare 2,2-disubstituted-2,3-dihydro~l,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-l,4-benzodioxins, as key synthetic intermediates, are reported. These new synthetic approaches require Lewis acid BF3-Et20 mediated nucleophilic substitution reaction or cy