A New Synthesis of 2-Deoxy-D-ribose
β Scribed by GORIN, P. A. J.; JONES, J. K. N.
- Book ID
- 109573807
- Publisher
- Nature Publishing Group
- Year
- 1953
- Tongue
- English
- Weight
- 210 KB
- Volume
- 172
- Category
- Article
- ISSN
- 0028-0836
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A 2-deoxy-ribose-type 1-N-iminosugar 5 was synthesized, in multi-gram scale, from fumaric acid monoethyl ester employing Sharpless asymmetric epoxidation followed by a Lewis acid-catalyzed (Yamamoto's aluminum reagent) cyanide epoxy ring-opening reactions.