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A new synthesis of 1,1-diphenyl-3-arylisoquinolin-4-ones by the novel cyclization of 2-azabuta-1,3-dienes.

✍ Scribed by Diego Armesto; William M. Horspool; Fernando Langa; Maria J. Ortiz; Rafael Perez-Ossorio; Santiago Romano


Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
163 KB
Volume
26
Category
Article
ISSN
0040-4039

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## Abstract magnified image A simple one‐step method for preparation of novel 1,3,4‐triaryl‐3,4‐dihydropyrimidin‐2(1__H__)‐ones has been developed by reaction of aromatic isocyanates with β‐arylamino‐1‐phenylpropan‐1‐ones in refluxing toluene in the presence of KHSO~4~ and HCl.