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A convenient synthesis of novel 1,3,4-triaryl-3,4-dihydropyrimidin-2(1H)-ones by cyclization of aromatic isocyanates with β-arylamino-1-phenylpropan-1-ones

✍ Scribed by Yongzhou Hu; Xiuyang Lu; Na Xue


Publisher
Journal of Heterocyclic Chemistry
Year
2008
Tongue
English
Weight
259 KB
Volume
45
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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A simple one‐step method for preparation of novel 1,3,4‐triaryl‐3,4‐dihydropyrimidin‐2(1__H__)‐ones has been developed by reaction of aromatic isocyanates with β‐arylamino‐1‐phenylpropan‐1‐ones in refluxing toluene in the presence of KHSO~4~ and HCl.


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