Starting from the (R)-(-)-phenylglycinol derivative (I), the stereoselective synthesis of polyhydroxylated pyrrolidines [cf. (VIII)] and the indolizidine (XII) is based on the diastereoselective condensation of the chiral silyloxypyrrole (III) with aldehydes (IV). The preparation of the indolizidine
✦ LIBER ✦
A New Strategy for the Diastereoselective Synthesis of Polyfunctionalized Pyrrolidines.
✍ Scribed by Andrew S. Davis; Nicole J. Gates; Karl B. Lindsay; Minyan Tang; Stephen G. Pyne
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 118 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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