A new standard nomenclature for proteins related to Apx and Shroom
β Scribed by Olivier Hagens; Andrea Ballabio; Vera Kalscheuer; Jean-Pierre Kraehenbuhl; M Vittoria Schiaffino; Peter Smith; Olivier Staub; Jeff Hildebrand; John B Wallingford
- Book ID
- 104492563
- Publisher
- BioMed Central
- Year
- 2006
- Tongue
- English
- Weight
- 115 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1471-2121
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β¦ Synopsis
Shroom is a recently-described regulator of cell shape changes in the developing nervous system. This protein is a member of a small family of related proteins that are defined by sequence similarity and in most cases by some link to the actin cytoskeleton. At present these proteins are named Shroom, APX, APXL, and KIAA1202. In light of the growing interest in this family of proteins, we propose here a new standard nomenclature.
π SIMILAR VOLUMES
Inspection of the complete Saccharomyces cerevisiae genome sequence and analysis of the actin-related proteins (ARPs) found therein revealed seven proteins, in addition to the previously designated actin-related proteins Arp1, Arp2 and Arp3, which contained substantial blocks of conservation relativ