In the course of systematic study of the chlroptlcal propertles of DNP-c(amino acids, we noted that CD-spectra of DNP-aromatlc amino acids show characterlstlc pattern, which 1s somewhat different from those of Na,Nw-dl-DNPamino aclds1)'2). They have lower intensity and their shorter wavelength band
A new sensitive method for determining absolute configuration of α-amino acids: CD spectra of N-2,4-dinitrophenyl-α-amino acylanilides
✍ Scribed by Masao Kawai; Ukon Nagai
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 123 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Recently we reported a method useful for determining absolute configuration of aromatic o-amino acids in micromolar quantities. The method is based on the
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## Abstract Enantiopure α‐amino acids were converted to 4‐substituted 2‐aryl‐ and 2‐alkyl‐5(4__H__)‐oxazolones under partial racemization. These nonracemic mixtures were dissolved in CDCl~3~, an equimolar amount of the chiral dirhodium complex $Rh^{\rm (II)}\_{2}$[(__R__)− (+)− MTPA]~4~ (MTPA‐H = M
The absolute configuration of beta-hydroxy-alpha-amino acids was studied by CD exciton chirality method using 7-diethylaminocoumarin-3-carboxylate as a red-shifted chromophore. The CD spectra of bischromophoric derivatives of (S)-serine and (2S,3R)-threonine methyl esters (2 and 7) were compared wit
Aromatic B-amino acids were converted to the Dnp derivatives, and aliphatic ones to Dnp-pMA derivatives. The sign of the Cotton effect near 400 nm reflected the configuration at the B-position without exception. Thus, the relation seems to afford a new reliable method for determining the absolute