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A new secondary ion mass spectrometry (SIMS) system with high-intensity cluster ion source

✍ Scribed by Jiro Matsuo; Chihiro Okubo; Toshio Seki; Takaaki Aoki; Noriaki Toyoda; Isao Yamada


Book ID
113822930
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
393 KB
Volume
219-220
Category
Article
ISSN
0168-583X

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✍ Alain Brunelle; David Touboul; Olivier LaprΓ©vote πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 873 KB

## Abstract Time‐of‐flight secondary ion mass spectrometry (TOF‐SIMS) using liquid metal ion guns (LMIGs) is now sensitive enough to produce molecular‐ion images directly from biological tissue samples. Primary cluster ions strike a spot on the sample to produce a mass spectrum. An image of this sa

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The secondary ion mass spectrometry (SIMS) microscope has opened new fields in biological investigation because of its ability to map chemical elements that are either naturally present in tissue or introduced for diagnostic or therapeutic purposes. In this review, we will describe our attempts to l