A new secondary ion mass spectrometry (SIMS) system with high-intensity cluster ion source
β Scribed by Jiro Matsuo; Chihiro Okubo; Toshio Seki; Takaaki Aoki; Noriaki Toyoda; Isao Yamada
- Book ID
- 113822930
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 393 KB
- Volume
- 219-220
- Category
- Article
- ISSN
- 0168-583X
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## Abstract Timeβofβflight secondary ion mass spectrometry (TOFβSIMS) using liquid metal ion guns (LMIGs) is now sensitive enough to produce molecularβion images directly from biological tissue samples. Primary cluster ions strike a spot on the sample to produce a mass spectrum. An image of this sa
The secondary ion mass spectrometry (SIMS) microscope has opened new fields in biological investigation because of its ability to map chemical elements that are either naturally present in tissue or introduced for diagnostic or therapeutic purposes. In this review, we will describe our attempts to l