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A new screening protocol combining urine β-core fragment and ultrasonography for Down syndrome detection

✍ Scribed by R.O. Bahado-Singh; U.A. Oz; O. Deren; E. Acuna; D. Cermik; M.J. Mahoney; L. Cole

Book ID
113985790
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
115 KB
Volume
178
Category
Article
ISSN
1097-6868

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Two recent publications by Cuckle et al., and one each by Canick et al. and Kellner et al., describe the use of urine beta-core fragment measurements as a screening test for Down syndrome pregnancies. Median levels of over 5.4 MOM were reported for cases of Down syndrome, with an over 72 per cent de

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Variable results have been reported using urine -core fragment as a marker for fetal Down syndrome. Initial studies by Cuckle et al. (1994) and Canick et al. (1995) indicated that -core fragment was an outstanding marker, detecting >80 per cent of Down syndrome cases. Since these reports, widely var

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