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A New Screen for Combinatorial Catalysis; On-Bead Testing in Agarose Gel

✍ Scribed by Michael Müller; Trevor W. Mathers; Anthony P. Davis


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
116 KB
Volume
113
Category
Article
ISSN
0044-8249

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A New Screen for Combinatorial Catalysis
✍ Michael Müller; Trevor W. Mathers; Anthony P. Davis 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB 👁 2 views

Catalytic beads are readily distinguished from inactive controls in a method which exploits the localizing potential of a gel. A useful variant employs an acid/base indicator to detect the pH change on ester hydrolysis. Precipitation of the acidified indicator (red) creates an especially strong cont