A new synthetic route to tropane alkaloi
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Hideo Iida; Yohya Watanabe; Chihiro Kibayashi
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Article
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1984
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Elsevier Science
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French
β 227 KB
Pseudotropine and tropacocaine have been synthesized by a facile route involving the [4 + 21 nitroso cycloaddition followed by interna1 Sn2 displacement. The tropane class of alkaloids have continued to elicit the unabated interests among organic chemists because of their pharmacological significanc