A New Role for Polyketides
✍ Scribed by Jürgen Rohr
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 123 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0044-8249
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Crotonyl-CoA reductase (CCR), which catalyzes the reduction of crotonyl-CoA to butyryl-CoA, is common to most streptomycetes and appears to be inducible by either lysine or its catabolites in Streptomyces cinnamonensis grown in chemically defined medium. A major role of CCR in providing butyryl-CoA
## Abstract Four new polyketides, botryosphaerones A–D (**1**–**4**, resp.), were obtained from the fermentation culture of __Botryosphaeria australis__ strain ZJ12‐1A, together with four known compounds, __O__‐methylasparvenone (**5**), 6‐ethyl‐2,7‐dimethoxyjuglon (**6**) and its monoacetyl deriva