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A New Role for Corticotropin-Releasing Factor Receptor-2: Suppression of Vascularization

✍ Scribed by Tracy L Bale; Frank J Giordano; Wylie W Vale

Book ID: 114342076
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 683 KB
Volume: 13
Category: Article
ISSN: 1050-1738
DOI: 10.1016/s1050-1738(02)00214-1

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## Abstract Corticotropin releasing factor (CRF), localized in afferent inputs to the cerebellum, binds to two receptors defined as the Type 1 (CRF‐R1) and the Type 2 (CRF‐R2α). CRF‐R1 has been localized to the cerebellum, as has a truncated isoform of CRF‐R2α. Evidence for the presence of the full