A new reductive procedure for the preparation of vicinal diamines and monoamines
β Scribed by Sang-Hun Jung; Harold Kohn
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 216 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
sumnary: Selective reductive procedures for the preparation of vicinal diamines and rrpncmines fran alkyl bromxyanamides are described.
The frequent occurrence of the vicinal diamine functionality (1, in important naturally occurring compounds and medicinal agents renders this group a worthy synthetic target.
Currently, few general methods exist for the preparation of vicinal diamines.3 Recently we reported4 a novel diamination procedure which utilized unactivated olefins (11, cyanamide (11, and N-br~succinimide (Scheme 1). The overall reaction was stereospecific and permitted
π SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
A novel method is reported for the transformation of vicinal diols to olefins. This methodology consists in the conversion of iodothiocarbonates such as 16 to olefin 17 with phenyl lithium in excellent yield. Compounds 7 and 12 were prepared by this methodology in order to determine if they would be
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v