A new reductive acetylation of sulphinic acids and its application to the synthesis of 2-acetylthio-4-oxoazetidines
β Scribed by James R. Irving; Ettore Perrone; Richard J. Stoodley
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 197 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The sulphinic acid function of i4-oxoazetidin-2-yl)sulphinic acids is transformed into the acetylthio moiety by sequential reactions involving thionyl chloride, thioacetic acid and triphenylphosphine.
π SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
Protected S-pyroglutamic acid can be deprotonated specifically at the y-position. The resulting enolate can be converted into y-carboxyglutamic acid in optically pure form. The naturally occurring aminoacid r\_carboxyglutamtc acid (1; Gla) is a constituent of prothrombin and other proteins.1 The nat