Synthesis of a New N-Acetyl Thiazolidinethione Reagent and Its Application to a Highly Selective Asymmetric Acetate Aldol Reaction.
β Scribed by Yingchao Zhang; Tarek Sammakia
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 29 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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## Abstract The domino reaction of 2,3βepoxyβ1βalcohol derivatives, namely tetrasubstituted 2,3βepoxyβ1βalcohols and 2β or 3βalkyl trisubstituted 2,3βepoxyβ1βalcohols, with PhI(OCOCF~3~)~2~ in the presence of H~2~O is described in detail. In this reaction, several types of lactol derivatives can be