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A New Reactivity-Based One-Pot Synthesis of N -Acetyllactosamine Oligomers

✍ Scribed by Mong, Tony K.-K.; Huang, Cheng-Yuan; Wong, Chi-Huey

Book ID
126921390
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
190 KB
Volume
68
Category
Article
ISSN
0022-3263

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## Abstract Poly‐__N__‐acetyllactosamine (Poly‐LacNAc, [3Galβ1,4GlcNAcβ1]~n~) glycans play an essential role in carbohydrate‐protein interactions. The synthesis of poly‐LacNAc, both chemical and enzymatic, is typically characterized by high losses of product during sequential synthesis, due to depr