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A New Reactivity-Based One-Pot Synthesis of N-Acetyllactosamine Oligomers.

✍ Scribed by Tony K.-K. Mong; Cheng-Yuan Huang; Chi-Huey Wong

Publisher
John Wiley and Sons
Year
2003
Weight
56 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract Poly‐__N__‐acetyllactosamine (Poly‐LacNAc, [3Galβ1,4GlcNAcβ1]~n~) glycans play an essential role in carbohydrate‐protein interactions. The synthesis of poly‐LacNAc, both chemical and enzymatic, is typically characterized by high losses of product during sequential synthesis, due to depr