Efficient synthesis of (ยฑ)-N-BOC-exo-2-(
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Satendra Singh; Garo P. Basmadjian
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Article
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1997
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Elsevier Science
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French
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heptane, an important intermediate for the synthesis of epibatidine and its analogs was efficiently synthesized from N-BOC-exo-2-(methoxycarbonyl)-7azabicyclo[2.2.1]hepta-2,5-diene (5) via hydrogenation followed by reductive dehalogenation or via hydrodehalogenation followed by epimerization. The di