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A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer’s disease

✍ Scribed by Federico Licastro; Martina Chiappelli; Luigi M.E. Grimaldi; Kevin Morgan; Noor Kalsheker; Elena Calabrese; Alistair Ritchie; Elisa Porcellini; Giuliana Salani; Massimo Franceschi; Nicola Canal

Book ID
116780513
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
78 KB
Volume
26
Category
Article
ISSN
0197-4580

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An association study of polymorphisms in the alpha-antichymotrypsin gene for Alzheimer disease in Han-Chinese
✍ Guangxun Meng; Jinduo Yuan; Liguo An; Jialei Gong; Hanmin Zhu; Sisong Cui; Zheng 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 31 KB 👁 2 views

Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) and DNA sequencing were employed to screen the coding region of the alpha-antichymotrypsin (AACT) gene in Han-Chinese population for polymorphism possibly associated with Alzheimer's disease (AD). Consequently, seven polymo