A new procedure for α-alkoxyalkylation of α,β -unsaturated ketones
✍ Scribed by M. Suzuki; T. Kawagishi; R. Noyori
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 223 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
A one-pot procedure for c1 -alkoxyalkylation of o., B -unsaturated icetones has been devised, which by combination with the organocopper conjugate addition reaction provides a new tool for vicinal carba-condensation of enones.
📜 SIMILAR VOLUMES
Akstra~. ~l~-Unsaturated ketones are aziridinated by [(arenesulphonyl)oxy]carbamates and CaO (or Cs2CO3) or by N3CO2Et photolysis. A remote chiral center induced up m 74% ~e. Bis-unsaturated subeuates showed scarce regioselectivity under all conditions.
BIRCH' demonstrated in 1950 that a steroidal a,p-unsaturated ketone (I) may be deconjugated to its p,y-unsaturated ketone isomer (III) by irreversible protonation of the conjugate anion (II), however, the requisite anion has been prepared only by indirect means (e.g. through the enol acetate, 132 fr
## Abstract For Abstract see ChemInform Abstract in Full Text.
a-Fluoro-a,b-unsaturated ketones were prepared from trifluoromethyl ketones via a sequence involving Mg metal promoted successive double defluorination. Trifluoromethyl ketones were transformed to b,b-difluoroenol silyl ethers which were then coupled with aldehydes and ketones to b-hydroxy-a,a-diflu