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A new phenol synthesis from the rhodium (I) catalyzed reaction of cyclopropenes and alkynes

✍ Scribed by Padwa, Albert; Xu, Simon L.


Book ID
121386810
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
266 KB
Volume
114
Category
Article
ISSN
0002-7863

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Rhodium(I)-catalyzed addition of phenols
✍ Hugues BienaymΓ©; Jean-Erick Ancel *; Pierre Meilland; Jean-Pierre Simonato πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 145 KB

A highly convergent and atom-economical synthesis of (dl)-[Ξ±]-tocopherol (vitamin E) is proposed, the realization of which was made possible by the discovery of the regioselective Rh(I)-catalyzed arylation of Ξ²-springene with trimethylhydroquinone. Other phenolic compounds and 2-substituted-1,3-dien